How can pregnancy impact systemic lupus erythematosus?

Pregnancy can significantly affect systemic lupus erythematosus (SLE), and it is well-documented that it can induce or exacerbate symptoms of the disease in some individuals. Hormonal changes during pregnancy, especially the increase in estrogen, can influence the immune system and potentially lead to flare-ups of lupus symptoms.

Many women with SLE experience increased disease activity during pregnancy, particularly in the second and third trimesters when the immune system undergoes substantial changes. Symptoms may vary widely, including joint pain, skin rashes, and systemic issues affecting organs such as the kidneys or heart.

Understanding the potential for exacerbation is critical for managing patients with lupus who are considering pregnancy. Close monitoring and planning with a healthcare provider can help address and mitigate these risks. Thus, recognizing that pregnancy can indeed impact SLE by inducing or worsening its symptoms is essential for optimal patient care.