How can SLE impact pregnancy outcomes?

Systemic Lupus Erythematosus (SLE) is an autoimmune disease that can significantly impact pregnancy outcomes. One of the primary concerns in managing a pregnancy in a patient with SLE is the increased risk for fetal complications. This includes issues such as preterm birth, low birth weight, and potentially serious conditions like neonatal lupus, which can affect the baby's heart.

The presence of certain antibodies, such as anti-Ro (SSA) and anti-La (SSB), commonly associated with SLE, can cross the placenta and affect fetal development. Additionally, active disease in the mother during pregnancy raises the risk for adverse outcomes, including preeclampsia and increased maternal complications. Therefore, proper management and monitoring of SLE during pregnancy are crucial to minimize these risks and optimize outcomes for both the mother and the baby.

Considering the other options, stating that SLE has no effect on pregnancy ignores the complexities and associated risks involved. Claiming that it always results in miscarriage overstates the matter, as many women with SLE can and do have successful pregnancies with appropriate care. Lastly, suggesting that it guarantees healthy deliveries fails to acknowledge the potential complications that can arise from the disease. Thus, recognizing the increased risks for fetal complications is the