How does sunlight exposure affect SLE patients?

Sunlight exposure has a significant impact on patients with Systemic Lupus Erythematosus (SLE), primarily because ultraviolet (UV) radiation can exacerbate symptoms and trigger disease flares. Many individuals with SLE experience photosensitivity, where exposure to sunlight leads to the worsening of skin lesions and systemic symptoms. This phenomenon occurs because UV radiation can induce the production of autoantibodies, which play a critical role in the pathology of SLE.

In many cases, patients may find that their symptoms worsen after sun exposure, leading to increased inflammation, joint pain, fatigue, and even exacerbations of neuropsychiatric symptoms. Thus, it is essential for SLE patients to take precautions against sunlight, such as wearing protective clothing, applying sunscreen, and limiting sun exposure to help manage their condition and reduce flare-ups.