What does the term "arctic syndrome" refer to in relation to SLE?

The term "arctic syndrome" in relation to Systemic Lupus Erythematosus (SLE) refers to the overlapping of SLE with other autoimmune conditions. This phenomenon can be observed in patients who present symptoms or features that are common not just to SLE but also to other autoimmune disorders.

When individuals have overlapping autoimmunity, they might exhibit a combination of symptoms that align with multiple conditions, such as rheumatoid arthritis or Sjögren's syndrome alongside SLE. This connection acknowledges the complexity of autoimmune diseases and their interplay, pointing to the idea that a single patient can have manifestations from several autoimmune disorders simultaneously.

Understanding this concept is crucial for proper diagnosis and treatment, as it allows clinicians to recognize the broader spectrum of autoimmune disorders and manage patient care holistically. The term captures the interconnected nature of these conditions rather than indicating a specific condition or treatment related to cold environments or a particular medication.