What does the term "flare" signify in the context of SLE?

In the context of Systemic Lupus Erythematosus (SLE), the term "flare" specifically refers to an exacerbation of symptoms. This occurs when a person experiences a worsening of their disease following a period of stability or remission. During a flare, individuals may see an increase in symptoms such as joint pain, fatigue, skin rashes, or other manifestations of the disease, indicating that the immune system is more actively attacking the body's tissues at that time.

Understanding that a flare signifies an exacerbation is crucial for both patients and healthcare providers. It helps in recognizing the need for potential modifications in treatment strategies, including adjusting medication or initiating additional therapies. Monitoring for flares is an essential part of managing SLE, as they can vary in severity and duration, and early intervention can help mitigate potential complications.