What is a common symptom of SLE?

Fatigue is a hallmark symptom of Systemic Lupus Erythematosus (SLE) and is reported by a significant number of patients. This fatigue is often described as being more profound than typical tiredness, and it may not improve significantly with rest. In SLE, fatigue can be multifactorial; it may be related to the underlying disease activity, inflammation, and the psychological impact of managing a chronic illness. It can also be exacerbated by factors such as sleep disturbances or treatments like corticosteroids.

While persistent cough, chronic headaches, and vision problems can occur in some patients with SLE, they are not as universally recognized or prevalent as fatigue. The presence of fatigue in SLE is an important clinical feature that affects the quality of life of individuals living with the condition, making it a primary concern in both diagnosis and management.