What is Systemic Lupus Erythematosus (SLE)?

Systemic Lupus Erythematosus (SLE) is classified as an autoimmune disease where the immune system mistakenly targets and attacks the body’s own tissues and organs. This condition can affect various areas of the body, including the skin, joints, kidneys, heart, and blood cells, leading to a broad range of symptoms. The hallmark of SLE is the presence of autoantibodies, which are antibodies directed against the body’s own proteins, contributing to inflammation and damage in multiple organ systems.

The complexity of SLE is reflected in its diverse clinical manifestations, which can vary significantly from one individual to another. It is not caused by an infectious agent such as a virus, nor is it classified as a genetic disorder or a metabolic disorder. While genetic factors can contribute to the susceptibility of developing SLE, it does not inherently result in muscle tissue damage as seen in some genetic disorders. Similarly, it is not categorized under metabolic disorders that typically focus on hormonal imbalances. Understanding these distinctions is crucial in recognizing SLE as an autoimmune condition and differentiating it from other categories of diseases.