What is the role of antimalarials like hydroxychloroquine in SLE management?

Antimalarials, particularly hydroxychloroquine, play a crucial role in the management of systemic lupus erythematosus (SLE) by effectively treating skin and joint symptoms. This medication helps reduce the severity of these symptoms and can improve overall disease control. Hydroxychloroquine has anti-inflammatory properties, which can alleviate joint pain and swelling commonly associated with SLE. Additionally, it is effective against cutaneous manifestations of the disease, such as rashes and lesions, providing a dual benefit in managing both articular and dermatological symptoms.

Beyond symptomatic relief, using hydroxychloroquine has been associated with a reduction in disease flares and may have protective effects against some of the more severe manifestations of SLE, making it a cornerstone of long-term therapy. This use of hydroxychloroquine emphasizes its importance in improving the quality of life for patients with SLE by directly addressing some of the most distressing symptoms they face.