What psychiatric manifestation can occur in patients with systemic lupus erythematosus?

Patients with systemic lupus erythematosus (SLE) can experience a range of psychiatric manifestations due to the complex interplay between the disease, its effects on the central nervous system, and the psychological impact of living with a chronic illness. Psychosis is one such manifestation and can manifest as hallucinations, delusions, or severe mood disturbances.

In the context of SLE, psychosis may arise from autoimmune processes affecting the brain or as a side effect of certain medications used in treatment. It can significantly impact a patient's quality of life and functioning, making it essential for clinicians to recognize and address these symptoms as part of comprehensive care.

The other options do not align with recognized psychiatric manifestations of SLE. For example, memory enhancement is not a typical symptom associated with lupus; in fact, cognitive deficits, rather than enhancements, are often reported. Positive affect is generally not a symptom of SLE and is inconsistent with the nature of psychiatric disorders that may arise from chronic illness. Thus, identifying psychosis as a psychiatric manifestation specific to SLE captures an important aspect of the condition's potential impact on mental health.