What skin-related issues are commonly associated with systemic lupus erythematosus?

Systemic lupus erythematosus (SLE) is an autoimmune disease that commonly manifests in various ways, particularly affecting the skin. Rashes and photosensitivity are hallmark skin-related issues associated with SLE.

In SLE, patients frequently develop a characteristic butterfly rash across the cheeks and nose, known as a malar rash. This rash is often exacerbated by exposure to sunlight, which leads to photosensitivity. Individuals with photosensitivity may notice that their skin erupts into a rash or becomes inflamed after being in the sun, which is a direct result of their immune system's hyperreactivity to UV radiation.

While other options discuss various skin changes, they do not accurately reflect the skin-related manifestations that are most typically observed in systemic lupus erythematosus. Therefore, recognizing rashes and photosensitivity is crucial for diagnosis and management of the disease, making this the correct response.