What symptom is common in exacerbations of systemic lupus erythematosus (SLE)?

Joint stiffness is a common symptom experienced during exacerbations of systemic lupus erythematosus (SLE). This condition often leads to inflammation of the joints, which can result in pain and stiffness, particularly upon waking or after periods of inactivity. During flare-ups, patients may notice a worsening of these symptoms, which can significantly impact their mobility and quality of life.

In contrast, while persistent cough may occur in some patients due to associated pulmonary manifestations of lupus, it is not as directly tied to disease activity as joint stiffness. Elevated blood pressure can be a consequence of various factors related to SLE, including kidney involvement or medication side effects, but it is not a hallmark symptom of disease exacerbation. Skin rashes, while notable in lupus, often manifest differently—typically as a butterfly rash on the face or other areas—rather than specifically on the back, making joint stiffness a more representative symptom during flare-ups.