What symptom is commonly associated with an SLE flare?

Exacerbated fatigue is a hallmark symptom of a flare in systemic lupus erythematosus (SLE). During a flare, individuals often experience increased levels of fatigue due to the heightened autoimmune activity in their bodies. This fatigue is not just ordinary tiredness; it can be profound and debilitating, greatly impacting daily functioning and quality of life.

In the context of SLE, fatigue can stem from several factors, including inflammatory processes, stress on the body from the disease activity, potential anemia, and sleep disturbances often associated with lupus. Patients may notice that their usual level of energy dips significantly during a flare, making it a critical sign to monitor.

Other symptoms associated with SLE flares might include joint pain, rashes, and fever, but exacerbated fatigue is particularly indicative of increased disease activity. This understanding can guide both patients and healthcare providers in managing and treating SLE more effectively.