Which medication is commonly used in the treatment of systemic lupus erythematosus (SLE)?

Prednisone is commonly used in the treatment of systemic lupus erythematosus (SLE) due to its potent anti-inflammatory and immunosuppressive properties. SLE is an autoimmune disorder characterized by widespread inflammation, and corticosteroids like prednisone help to control this inflammation, alleviate symptoms, and prevent further tissue damage. Prednisone can effectively reduce the activity of the immune system, which is especially beneficial in managing flares of SLE.

In contrast, the other medications listed have different indications and uses. Ibuprofen, while it is an anti-inflammatory and can help manage pain and inflammation, is not a primary treatment option for SLE. It may be used for symptomatic relief but does not address the underlying autoimmune mechanisms. Amoxicillin is an antibiotic used to treat bacterial infections, with no role in managing autoimmune conditions like SLE. Levothyroxine is a thyroid hormone replacement medication used for hypothyroidism and does not have any therapeutic impact on lupus. Thus, prednisone stands out as the primary medication used in the management of SLE.