Which of the following factors can bring on an SLE flare-up?

Emotional stress is recognized as a significant trigger for flare-ups in individuals with Systemic Lupus Erythematosus (SLE). Stress can provoke an inflammatory response in the body, which may exacerbate the underlying autoimmune processes associated with lupus. The impact of psychological stress on the immune system can lead to heightened activity of lupus, resulting in increased symptoms and the potential for a flare.

Psychologically, stress can affect hormonal balances and immune function, making it a critical factor to manage for those living with SLE. Learning stress management techniques, such as mindfulness, relaxation exercises, or counseling, can be valuable tools for patients in maintaining their overall health and minimizing flare-ups.

In contrast, factors like sleep, physical exercise, and a healthy diet are generally considered beneficial for lupus patients. Adequate sleep can help in recovery and reduce fatigue, regular physical activity can improve overall health and well-being, and a nutritious diet supports the immune system and enhances energy levels. Thus, these factors do not usually contribute to flare-ups but rather support disease management.