Which of the following is a common early manifestation of SLE?

Extreme fatigue is indeed a common early manifestation of systemic lupus erythematosus (SLE). Many patients report feeling an overwhelming sense of tiredness that does not improve with rest. This fatigue can significantly impact daily activities and quality of life.

In SLE, fatigue may result from a combination of factors, including the body’s autoimmune response, inflammation, and possibly the effects of medications. This symptom can be one of the earliest indicators of lupus, often prompting individuals to seek medical advice. Recognizing fatigue as a significant symptom can help in the early diagnosis and management of the disease.

High blood pressure, while it can occur in lupus patients, is not typically one of the earliest signs of the disease. Joint immobilization is more indicative of inflammation or damage due to chronic disease rather than a primary early symptom. Vision problems can occur in lupus but are generally more related to specific organ involvement and not found as a major early presenting symptom.