Which of the following symptoms is NOT typically associated with systemic lupus erythematosus?

Systemic lupus erythematosus (SLE) is characterized by a variety of symptoms that can affect multiple organ systems. The butterfly rash, joint pain, and fatigue are all common manifestations of the disease. The butterfly rash, or malar rash, is a distinctive skin eruption that appears over the cheeks and bridge of the nose in many patients. Joint pain is also very common, as many individuals with lupus experience arthritis or arthralgia. Fatigue is a frequently reported symptom among those with SLE, often resulting from both the disease process and related inflammation.

Chronic cough, while it can occur if there are respiratory complications associated with lupus, is not a typical symptom of SLE itself. Instead, it may indicate other underlying conditions or complications, such as lung involvement or infections, rather than being a primary symptom of the disease. This distinction helps clarify why chronic cough is not regularly associated with systemic lupus erythematosus, making it the correct answer in this context.